Dental Ozone Therapy
Written and clinically reviewed by Dr. Yuriy May, DMD · Last reviewed
Ozone Therapy in Dentistry, Disinfecting, Sterilizing and addresing Tooth Infections. How does ozone in biological dentistry help heal or help resolve infections? Understanding what ozone can and cannot achieve is important, ozone alone cannot treat tooth decay, or root canal infections. Ozone is instead a valuable biological therapeutic tool used in Dr. May’s practice with every dental procedure to disinfect dental areas, reduce biofilm, remove and disinfect bacteria, and clean out infected surgical sites and inflamed periodontal and gingival pockets. When used in conjunction with other biological protocols such as PRF and laser, ozone is an incredibly important and powerful tool for removing infection, promoting angiogenesis and osteogenesis, and reducing inflammation.
Dental Caries & Ozone Therapy
How does Ozone Therapy work on Dental Caries, Physiology and Biochemistry
When ozone enters the system it reacts with biomolecules (PUFA, antioxidants) present in the plasma, the reaction yields hydrogen peroxide (among other possible ROS) and lipid oxidation products (LOPS).
The sudden rise in plasma concentration of hydrogen peroxide generates a gradient, which causes its rapid transfer into blood cells where, in a few seconds, it activates several biochemical processes and simultaneously undergoes reduction to water by the efficient intracellular antioxidant system of the body.
Dr. Yuriy May generates ozone gas and ozone water in Connecticut office daily
While ozone gas is created in a number of different ways, including ultra violet (UV) light, corona discharge of electricity through an oxygen stream (including air), and via chemical methods. To create Ozone Gas Dr. Yuriy May uses the most robust and high-quality form of ozone gas generation, using an industrial size, commercial grade ozone generator. Dr. May’s ozone generator pumps the environments filtered ambient air (oxygen) through an air gap between a high voltage electrode and a stainless steel grounding electrode. During the passing of the air, an “energy field of electrons” is created by the high voltage electrode and instantly converts oxygen molecules (O2) molecules into ozone molecules (O3).
Other Applications of Ozone Therapy:
Major Ozone Autohemotherapy (AHT)
This term indicates the classical and unsurpassed procedure in which blood is withdrawn from the body, mixed with ozone gas, and then injects it back into the body through a vein or muscle by IV or intravenous injection (major AHT) or (minor AHT) into the donor. “Major” and “minor” are only meant to indicate a different volume of blood: 50-100 ml for the former and 5-10 ml for the latter.
Ozone Gas Rectal Insufflation (RI)
Payr and Aubourg, in 1936, introduced a mixture of ozone and oxygen into the rectum and absorbed in the body through the intestine. This method is used for a variety of health illness with various symptoms including leaky gut and considered one of the safest methods of administration. It does cause some gassy ozone smells in a room post-anal insufflation! Watch out!
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About Dr. Yuriy May
Widely sought after for his precision and leadership in biological oral surgery and zirconia implantology, Dr. Yuriy May is recognized as an accomplished leader in metal-free, biologically driven dentistry. With over 14 years of clinical experience, his work is defined by uncompromising standards, refined surgical execution, and outcomes that support both oral and systemic health.
Dr. May holds advanced certifications and training in zirconia implantology from programs ranging from IAOCI and Tufts University, is Board Certified as a Naturopathic Dentist by the ANMCB, and is a distinguished Ceramic Implant Ambassador for SDS, an honor reserved for clinicians shaping the future of ceramic implant science.
A respected educator and international lecturer, Dr. May has presented extraordinary ceramic implant cases to dentists worldwide, including the JCCI in Switzerland, and has served as an instructor in the Ceramic Implant Program at ACIMD. He lectures nationally, publishes complex metal-free surgical cases, and serves as a Board Member of the IAOCI (International Academy of Oral Ceramic Implantology). Dr. May has recently become a Fellow of the AAID (American Academy of Implant Dentistry), one of the few focusing solely on zirconia dental implants, and has been and an Accredited S.M.A.R.T. Certified member of the IAOMT for many years. He is also a Certified Biological Dentist with the IABDM, reflecting his commitment to removing root canal infections and to mercury-safe, evidence-based biological protocols.
Dr. May’s reputation, results, and excellence in ceramic implant dentistry have made him a destination provider for patients and referring clinicians seeking the highest level of ceramic implant surgery and biological dental care.
DMD, FAAID, IBDM, AIAOMT, CIABDM
Fellow, American Academy of Implant Dentistry
ANMCB Board Certified Naturopathic Dentist
What patients say about Dr. May
Rated 4.8 out of 5 from 215 Google reviews of Natural Dentistry and Ceramic Implants, a biological destination clinic just outside of New York. Read all reviews on Google
Content addressing the topics below is provided for general educational discussion only. It is not medical or dental advice, does not diagnose any condition, and does not recommend any treatment for any individual. You must not rely on this content to make healthcare decisions. Diagnosis and treatment decisions require an in-person evaluation, appropriate records, and a clinician’s professional judgment based on your specific facts.
No guarantees; outcomes vary. Any discussion of potential benefits, risks, timelines, or outcomes is general and not a promise, guarantee, or prediction for any individual.
No definitive causation claims. Where mechanisms, systemic effects, or cause-and-effect relationships are discussed, they may reflect hypotheses, evolving evidence, clinical experience, or differing views within the broader community; they are not statements of universal fact for every patient.
Adjunctive concept; not a guarantee. Any discussion of ozone use in dentistry (including for irrigation, disinfection, wound support, or surgical adjuncts) is informational only. It is not a promise of efficacy or a substitute for standard evaluation and care planning.
Individualized appropriateness. Whether ozone is appropriate depends on patient-specific factors and clinical judgment after in-person evaluation.